diff --git a/Marlin/src/core/serial_base.h b/Marlin/src/core/serial_base.h
index a8700f3d23..07bed55b35 100644
--- a/Marlin/src/core/serial_base.h
+++ b/Marlin/src/core/serial_base.h
@@ -228,7 +228,7 @@ struct SerialBase {
     // Handle negative numbers
     if (number < 0.0) {
       write('-');
-      number = -number;
+      number *= -1;
     }
 
     // Round correctly so that print(1.999, 2) prints as "2.00"
diff --git a/Marlin/src/gcode/calibrate/G34_M422.cpp b/Marlin/src/gcode/calibrate/G34_M422.cpp
index 1ac58cc894..6c367ad882 100644
--- a/Marlin/src/gcode/calibrate/G34_M422.cpp
+++ b/Marlin/src/gcode/calibrate/G34_M422.cpp
@@ -390,7 +390,7 @@ void GcodeSuite::G34() {
             // Decreasing accuracy was detected so move was inverted.
             // Will match reversed Z steppers on dual steppers. Triple will need more work to map.
             if (adjustment_reverse) {
-              z_align_move = -z_align_move;
+              z_align_move *= -1;
               if (DEBUGGING(LEVELING)) DEBUG_ECHOLNPGM("> Z", zstepper + 1, " correction reversed to ", z_align_move);
             }
           #endif
diff --git a/Marlin/src/lcd/extui/dgus/fysetc/DGUSScreenHandler.cpp b/Marlin/src/lcd/extui/dgus/fysetc/DGUSScreenHandler.cpp
index be0e60a8df..f4c7db544b 100644
--- a/Marlin/src/lcd/extui/dgus/fysetc/DGUSScreenHandler.cpp
+++ b/Marlin/src/lcd/extui/dgus/fysetc/DGUSScreenHandler.cpp
@@ -205,7 +205,7 @@ void DGUSScreenHandler::handleManualMove(DGUS_VP_Variable &var, void *val_ptr) {
     const uint16_t backup_speed = MMS_TO_MMM(feedrate_mm_s);
     char sign[] = "\0";
     int16_t value = movevalue / 100;
-    if (movevalue < 0) { value = -value; sign[0] = '-'; }
+    if (movevalue < 0) { value *= -1; sign[0] = '-'; }
     int16_t fraction = ABS(movevalue) % 100;
     snprintf_P(buf, 32, PSTR("G0 %c%s%d.%02d F%d"), axiscode, sign, value, fraction, speed);
     queue.enqueue_one_now(buf);
diff --git a/Marlin/src/lcd/extui/dgus/hiprecy/DGUSScreenHandler.cpp b/Marlin/src/lcd/extui/dgus/hiprecy/DGUSScreenHandler.cpp
index 297c71f8a9..a62d3a2ffc 100644
--- a/Marlin/src/lcd/extui/dgus/hiprecy/DGUSScreenHandler.cpp
+++ b/Marlin/src/lcd/extui/dgus/hiprecy/DGUSScreenHandler.cpp
@@ -207,7 +207,7 @@ void DGUSScreenHandler::handleManualMove(DGUS_VP_Variable &var, void *val_ptr) {
     const uint16_t backup_speed = MMS_TO_MMM(feedrate_mm_s);
     char sign[] = "\0";
     int16_t value = movevalue / 100;
-    if (movevalue < 0) { value = -value; sign[0] = '-'; }
+    if (movevalue < 0) { value *= -1; sign[0] = '-'; }
     int16_t fraction = ABS(movevalue) % 100;
     snprintf_P(buf, 32, PSTR("G0 %c%s%d.%02d F%d"), axiscode, sign, value, fraction, speed);
     queue.enqueue_one_now(buf);
diff --git a/Marlin/src/lcd/extui/dgus/mks/DGUSScreenHandler.cpp b/Marlin/src/lcd/extui/dgus/mks/DGUSScreenHandler.cpp
index 010e1be381..2965d75da3 100644
--- a/Marlin/src/lcd/extui/dgus/mks/DGUSScreenHandler.cpp
+++ b/Marlin/src/lcd/extui/dgus/mks/DGUSScreenHandler.cpp
@@ -778,7 +778,7 @@ void DGUSScreenHandler::handleManualMove(DGUS_VP_Variable &var, void *val_ptr) {
   char buf[32]; // G1 X9999.99 F12345
   char sign[] = "\0";
   int16_t value = movevalue / 100;
-  if (movevalue < 0) { value = -value; sign[0] = '-'; }
+  if (movevalue < 0) { value *= -1; sign[0] = '-'; }
   const int16_t fraction = ABS(movevalue) % 100;
   snprintf_P(buf, 32, PSTR("G0 %c%s%d.%02d F%d"), axiscode, sign, value, fraction, speed);
   queue.enqueue_one_now(buf);
diff --git a/Marlin/src/lcd/extui/dgus/origin/DGUSScreenHandler.cpp b/Marlin/src/lcd/extui/dgus/origin/DGUSScreenHandler.cpp
index 0afc8a25ad..ac73c8cf65 100644
--- a/Marlin/src/lcd/extui/dgus/origin/DGUSScreenHandler.cpp
+++ b/Marlin/src/lcd/extui/dgus/origin/DGUSScreenHandler.cpp
@@ -207,7 +207,7 @@ void DGUSScreenHandler::handleManualMove(DGUS_VP_Variable &var, void *val_ptr) {
     const uint16_t backup_speed = MMS_TO_MMM(feedrate_mm_s);
     char sign[] = "\0";
     int16_t value = movevalue / 100;
-    if (movevalue < 0) { value = -value; sign[0] = '-'; }
+    if (movevalue < 0) { value *= -1; sign[0] = '-'; }
     int16_t fraction = ABS(movevalue) % 100;
     snprintf_P(buf, 32, PSTR("G0 %c%s%d.%02d F%d"), axiscode, sign, value, fraction, speed);
     queue.enqueue_one_now(buf);
diff --git a/Marlin/src/lcd/extui/dgus_reloaded/DGUSRxHandler.cpp b/Marlin/src/lcd/extui/dgus_reloaded/DGUSRxHandler.cpp
index e195654caa..6b2caadba0 100644
--- a/Marlin/src/lcd/extui/dgus_reloaded/DGUSRxHandler.cpp
+++ b/Marlin/src/lcd/extui/dgus_reloaded/DGUSRxHandler.cpp
@@ -676,11 +676,11 @@ void DGUSRxHandler::moveStep(DGUS_VP &vp, void *data_ptr) {
 
   switch (direction) {
     default: return;
-    case DGUS_Data::MoveDirection::XM: offset = -offset;
+    case DGUS_Data::MoveDirection::XM: offset *= -1;
     case DGUS_Data::MoveDirection::XP: axis = ExtUI::X; break;
-    case DGUS_Data::MoveDirection::YM: offset = -offset;
+    case DGUS_Data::MoveDirection::YM: offset *= -1;
     case DGUS_Data::MoveDirection::YP: axis = ExtUI::Y; break;
-    case DGUS_Data::MoveDirection::ZM: offset = -offset;
+    case DGUS_Data::MoveDirection::ZM: offset *= -1;
     case DGUS_Data::MoveDirection::ZP: axis = ExtUI::Z; break;
   }
 
diff --git a/Marlin/src/lcd/menu/game/brickout.cpp b/Marlin/src/lcd/menu/game/brickout.cpp
index 061e4e89c8..7b596a156f 100644
--- a/Marlin/src/lcd/menu/game/brickout.cpp
+++ b/Marlin/src/lcd/menu/game/brickout.cpp
@@ -53,7 +53,7 @@ void reset_ball() {
   bdat.ballv = FTOF(1.3f);
   bdat.ballh = -FTOF(1.25f);
   uint8_t bx = bdat.paddle_x + (PADDLE_W) / 2 + ball_dist;
-  if (bx >= GAME_WIDTH - 10) { bx -= ball_dist * 2; bdat.ballh = -bdat.ballh; }
+  if (bx >= GAME_WIDTH - 10) { bx -= ball_dist * 2; bdat.ballh *= -1; }
   bdat.ballx = BTOF(bx);
   bdat.hit_dir = -1;
 }
@@ -71,10 +71,10 @@ void BrickoutGame::game_screen() {
       // Provisionally update the ball position
       const fixed_t newx = bdat.ballx + bdat.ballh, newy = bdat.bally + bdat.ballv;  // current next position
       if (!WITHIN(newx, 0, BTOF(GAME_WIDTH - 1))) {    // out in x?
-        bdat.ballh = -bdat.ballh; _BUZZ(5, 220);            // bounce x
+        bdat.ballh *= -1; _BUZZ(5, 220);            // bounce x
       }
       if (newy < 0) {                                       // out in y?
-        bdat.ballv = -bdat.ballv; _BUZZ(5, 280);            // bounce v
+        bdat.ballv *= -1; _BUZZ(5, 280);            // bounce v
         bdat.hit_dir = 1;
       }
       // Did the ball go below the bottom?
@@ -96,8 +96,8 @@ void BrickoutGame::game_screen() {
           // If bricks are gone, go to reset state
           if (!--bdat.brick_count) game_state = 2;
           // Bounce the ball cleverly
-          if ((bdat.ballv < 0) == (bdat.hit_dir < 0)) { bdat.ballv = -bdat.ballv; bdat.ballh += fixed_t(random(-16, 16)); _BUZZ(5, 880); }
-                                       else { bdat.ballh = -bdat.ballh; bdat.ballv += fixed_t(random(-16, 16)); _BUZZ(5, 640); }
+          if ((bdat.ballv < 0) == (bdat.hit_dir < 0)) { bdat.ballv *= -1; bdat.ballh += fixed_t(random(-16, 16)); _BUZZ(5, 880); }
+                                       else { bdat.ballh *= -1; bdat.ballv += fixed_t(random(-16, 16)); _BUZZ(5, 640); }
         }
       }
       // Is the ball moving down and in paddle range?
@@ -107,13 +107,13 @@ void BrickoutGame::game_screen() {
         if (WITHIN(diff, 0, PADDLE_W - 1)) {
 
           // Reverse Y direction
-          bdat.ballv = -bdat.ballv; _BUZZ(3, 880);
+          bdat.ballv *= -1; _BUZZ(3, 880);
           bdat.hit_dir = -1;
 
           // Near edges affects X velocity
           const bool is_left_edge = (diff <= 1);
           if (is_left_edge || diff >= PADDLE_W-1 - 1) {
-            if ((bdat.ballh > 0) == is_left_edge) bdat.ballh = -bdat.ballh;
+            if ((bdat.ballh > 0) == is_left_edge) bdat.ballh *= -1;
           }
           else if (diff <= 3) {
             bdat.ballh += fixed_t(random(-64, 0));
diff --git a/Marlin/src/module/stepper.cpp b/Marlin/src/module/stepper.cpp
index 6be58e7bb5..cc0401cc6c 100644
--- a/Marlin/src/module/stepper.cpp
+++ b/Marlin/src/module/stepper.cpp
@@ -2515,7 +2515,7 @@ hal_timer_t Stepper::block_phase_isr() {
 
               if (forward_e != motor_direction(E_AXIS)) {
                 last_direction_bits.toggle(E_AXIS);
-                count_direction.e = -count_direction.e;
+                count_direction.e *= -1;
 
                 DIR_WAIT_BEFORE();
 
@@ -2876,7 +2876,7 @@ hal_timer_t Stepper::block_phase_isr() {
         la_interval = calc_timer_interval(uint32_t(ABS(step_rate)));
         if (forward_e != motor_direction(E_AXIS)) {
           last_direction_bits.toggle(E_AXIS);
-          count_direction.e = -count_direction.e;
+          count_direction.e *= -1;
           DIR_WAIT_BEFORE();
           E_APPLY_DIR(forward_e, false);
           TERN_(FT_MOTION, last_set_direction = last_direction_bits);